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Duloxetine
Clinical data
Trade namesCymbalta, many others [1]
AHFS/Drugs.comMonograph
MedlinePlusa604030
License dataEU  EMA:  by INN, US   FDA: duloxetine
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationOral
ATC codeN06AX21 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability~ 50% (32% to 80%)
Protein binding~ 95%
MetabolismLiver, two P450 isozymes, CYP2D6 and CYP1A2
Elimination half-life12.1 hours
Excretion70% in urine, 20% in feces

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Clindamycin is used to treat serious infections caused by bacteria. This may be fatal.

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Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. In Kombination mit Pyrimethamin ist es gegen Toxoplasma gondii wirksam.

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Send CR a Message. This is not a complete list of side effects and others may occur.

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This is not a complete list of side effects and others may occur. This may affect you if you have diabetes.

Shake the lotion well before each use to mix the medication evenly. Clindamycin will not treat a viral infection such as the flu or a common cold.

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Your doctor may have prescribed ReTrieve for another reason. Reversible rises in bilirubin and liver related enzymes.

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Mean steady state peak plasma concentrations Cssmax following doses of mg administered four-hourly were 3. Renal clearance of aciclovir is substantially greater than creatinine clearance, indicating that tubular secretion, in addition to glomerular filtration contributes to the renal elimination of the drug.

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This information is intended for use by health professionals 1. The registry findings have not shown an increase in the number of birth defects amongst aciclovir exposed subjects compared with the general population, and any birth defects showed no uniqueness or consistent pattern to suggest a common cause.

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These studies also indicate that this toxigenic clostridium is usually sensitive in vitro to vancomycin Clindamycin crosses the placenta
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Children aged two years and over should be given adult dosages and children below the age of two years should be given half the adult dose. Management Patients should be observed closely for signs of toxicity. Dosing should begin as early as possible after the start of an infection; for recurrent episodes this should preferably be during the prodromal period or when lesions first appear.

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Pharmacological properties Pharmacotherapeutic group: Most of the drug is excreted unchanged by the kidney.

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Vitamin K antagonists: Clindamycin may also be used for purposes not listed in this medication guide.

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However, this effect has not been clinically established and more studies need to be done to evaluate the true potential of this synergy. It is also effective in systemic or traumatic herpes infections, eczema herpeticum and herpes simplex meningitis.

This drug has been clinically proven to reduce the duration and the severity of outbreaks as well as limiting the occurrence of future outbreaks.

Call your doctor for medical advice about side effects. Read these directions and follow them carefully. In clinical trials with pregnant women, the systemic administration of clindamycin during the second and third trimesters has not been associated with an increased frequency of congenital abnormalities.

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