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    Evaluate the Subject according to inclusion and exclusion criteria see sections 3. The assumed standard deviation was

    The use of Clindamycin in combination with Benzoyl Peroxide Duac Gel is designed to decrease bacterial resistance when compared to clindamycin alone and has also been shown to produce a faster and clinically significant enhancement of the efficacy versus using clindamycin alone. The management of acne can be challenging due to the variability in response to treatment and the need for long-term therapy.

    The Evaluator should make no reference to Baseline or other previous visits when evaluating the Subject's facial acne.

    Laboratoires Galderma, S. If you fall pregnant while using Adapalene, the treatment must be discontinued and you should inform your doctor as soon as possible for a further follow-up. You may need to read it again.

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    If it is severe or troublesome, speak with your doctor If you experience any other symptoms which you think may be due to adapalene, speak with your doctor or pharmacist for further advice. Also avoid prolonged exposure to cold or wind. If you do get adapalene in your eyes, wash them with plenty of water and call your doctor.

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    Adapalene may cause the following side effects at the site of application. However, dosing compliance for these subjects will be computed based on number of days in the treatment phase of the study. Clindamycin suppresses the complement-derived chemotaxis of polymorphonuclear leukocytes in vitro, thereby reducing the potential for inflammation.

    At selected sites, take photographs of the face according to specific photographic procedures see Section 6.

    You may feel a slight warmth or stinging in the place where you applied adapalene. If your skin becomes very dry, it may help to use a moisturising cream preferably a fragrance-free and water-based cream.

    A new generation product, adapalene is a good my source in the treatment of acne vulgaris with less side effects and high efficacy confirmed by numerous clinical studies. Adaclene also contains preservatives methylparaben 0.

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    I regret it now. Applying more adapalene or applying adaplene more often than recommended will not speed up or improve results, but it may irritate your skin.


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    Follow the directions on your prescription label or the package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Check with your doctor or pharmacist if you are not sure.


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    Clean the skin with a mild soap or soap-free cleanser, rinse with water then apply a small amount with clean fingers and rub gently into the skin. If you used a pledget, discard it after use.


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